Prolotherapy: A Natural Approach to Pain Relief and Injury Recovery
If you're dealing with chronic joint pain, ligament injuries, or muscle instability—and you're looking for a non-surgical solution—prolotherapy might be the answer you've been searching for.
At The Regenerative Institute, Dr. Jonathan Pasma, DO, specializes in prolotherapy, a time-tested regenerative treatment that stimulates the body’s own healing mechanisms to repair damaged tissue and restore function.
What Is Prolotherapy?
Prolotherapy, short for "proliferation therapy," is a regenerative injection treatment that uses a natural solution—often containing dextrose (a type of sugar) and a local anesthetic—to stimulate the body’s healing response. It works by intentionally creating a mild, localized inflammation at the site of injury, which signals the body to send healing cells to strengthen and repair damaged soft tissue.
Unlike pain medications or steroid injections that simply mask symptoms, prolotherapy targets the root cause of pain by promoting long-term tissue repair and stability.
How Does Prolotherapy Work?
The healing process begins with the injection of the prolotherapy solution directly into the affected ligaments, tendons, or joints. Here’s a breakdown of how it works:
Injection – Dr. Pasma carefully identifies the injury site using anatomical landmarks or imaging guidance and injects the solution.
Inflammatory Response – The injected area experiences a mild, controlled inflammatory response, which kickstarts the body's natural healing.
Tissue Regeneration – Over time, the body lays down new collagen, strengthening weakened or damaged connective tissue.
Pain Reduction and Function Restoration – As the tissue heals and stabilizes, pain decreases, and function improves.
Patients typically undergo a series of treatments spaced a few weeks apart to achieve the best results.
What Is the Procedure Like?
At The Regenerative Institute, your prolotherapy journey begins with a comprehensive evaluation by Dr. Pasma to determine if you’re a good candidate. During the procedure:
You’ll lie comfortably in a treatment room.
Dr. Pasma cleans the injection area and applies a local anesthetic for comfort.
The prolotherapy solution is then injected with a fine needle into the targeted area.
The entire procedure takes about 30–45 minutes, and most patients resume normal activities the same day.
Some mild soreness or swelling at the injection site is normal and typically resolves within a few days.
What Conditions Can Prolotherapy Treat?
Prolotherapy is especially effective for musculoskeletal injuries and chronic pain, including:
Low back pain
Knee osteoarthritis
Shoulder instability or rotator cuff injuries
Tennis or golfer’s elbow
Hip pain
Neck pain
Ligament or tendon laxity
SI joint dysfunction
TMJ (jaw pain)
It is often used when other conservative treatments, like physical therapy or NSAIDs, haven’t provided long-term relief.
Why Choose The Regenerative Institute?
Dr. Jonathan Pasma brings extensive training in regenerative medicine and osteopathic principles to every treatment. His patient-first approach ensures that each care plan is tailored to your specific needs and long-term goals.
We prioritize evidence-based techniques, a comfortable experience, and comprehensive follow-up to help you heal naturally—without surgery.
Schedule Your Consultation Today
If you're ready to explore prolotherapy as a safe, effective alternative to surgery or long-term medication use, schedule a consultation with Dr. Jonathan Pasma at The Regenerative Institute. Let us help you return to a life of movement and vitality—naturally.
